Clinical Pipeline

Explore the Moleculogic-engineered therapeutic pipeline across KT-Biotech's MDC and FDC frameworks. Each candidate is built from logic-first blueprints that define behavior, constraints, and safety profiles for predictable clinical outcomes.

Pipeline Overview

Our pipeline leverages the deterministic Moleculogic engine to generate traceable, programmable drug blueprints. All compounds are logic-verified, entropy-stabilized, and regulation-aware before clinical development.

14
Total Logic Blueprints
8
Preclinical Candidates
11
Tier 1 Simulations
6
Therapeutic Areas

Moleculogic Advantage

Logic is the Drug. Simulation is the Proof. All molecules are generated by Moleculogic's deterministic engine with no random screening or guesswork.

Metal Drug Complex (MDC) Pipeline

Compound Name Indication Mechanism Status
Ru⁴⁺-Doxorubicin Oncology TME-pH-triggered release Tier 2 - Preclinical
Zn²⁺-Ivermectin Antiviral Metal-enhanced viral disruption Tier 2 - IND-Enabling
Cu²⁺-Histidine Neuroinflammation ROS-gated metal delivery Tier 1 - Simulated
Pt²⁺-GRX-REGEN-χ1 Hair Graying Reversal McSC redox modulation Tier 2 - Validated
Fe²⁺-20e-Ferrocene-X Redox Cancer Therapy 20-electron redox overload Tier 1 - Simulation
AIM001-MDC-χ2 Immuno-oncology (MITF+) Tumor-restricted ROS tuning Tier 2 - Simulated
QRX-HX1-MDC Renal Fibrosis Redox-NAD anti-fibrotic triad Tier 1 - Prototype
Featured MDC Compound

Pt²⁺-GRX-REGEN-χ1

A Tier 2 molecule derived from the GRX-REGEN-χ1 logic blueprint, targeting human hair graying reversal. It exploits redox triggers in melanocyte stem cells to reinitiate pigmentation through MITF and NAD⁺ cycling pathways.

ROS-MITF Modulated Redox-Governed Dose-Tunable
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Functional Drug Complex (FDC) Pipeline

Complex Name Indication Mechanism Status
Peptide-RNA ImmunoMod Autoimmune RNA-guided immune tuning Tier 2 - Concept Verified
OncoLogic-FDC Oncology Glyco-tagged nanoshell logic Tier 2 - Preclinical
FDC-AIM-χ1 Autoimmune (IL-2Rα) Treg selective activation Tier 2 - Simulated
FDC-AIM-χ2 Autoimmune + Muscle Thermogenesis + Tolerance Tier 1 - Simulation
FDC-TREGBAL-χ1 Treg Therapy IL-2 mutein replacement Tier 1 - Simulation
FDC-REGEN-χ2 Hair Graying Dual NAD/Stem niche logic Tier 1 - Simulated
Redunera CKD (T2D/HTN) Entropy-stabilized renal therapy Tier 4 - Simulation Verified
QRX-HX1-FDC Renal Fibrosis Ubiquinone/NAC/ATP modulation Tier 1 - Early Simulation
Featured FDC Compound

FDC-AIM-χ1

A Moleculogic Tier 2 blueprint that offers an IL-2Rα-selective immunologic rebalance strategy without systemic T cell activation. Includes entropy overlays for Foxp3, redox buffering, and Treg bias.

Autoimmune Targeting Logic-Gated Cytokine Simulation Validated
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Featured Tier 4 FDC Compound

Redunera

Redunera is a Tier 4 logic-enhanced therapeutic blueprint engineered for chronic kidney disease (CKD) patients with Type 2 Diabetes and Hypertension. It builds upon the QRX-3 backbone with layered entropy stabilization, renal-targeted delivery, and immune feedback suppression.

Entropy Layer
Taurine or Zn-histidine complex buffers metabolic drift
Targeting Layer
Dextran/polymer nanoparticle enhances renal specificity
Immune Feedback
Curcumin or calcitriol analog blocks NLRP3/TNFα rebound
Release Logic
ROS-triggered hydrogel activates only in diseased tissue
SEI Simulation Result: 82% ± 4% success rate under Tier 4 parameters
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Development Timeline

2025 Q1-Q2

GRX-REGEN-χ1 in vitro completed; QRX-HX1 preclinical modeling initiated; Tier 4 full simulation of Redunera logic stack completed.

2025 Q3

IND-enabling data package for Ru⁴⁺-Doxorubicin and FDC-AIM-χ1; Partner readiness evaluation for renal trials in Type 2 diabetic CKD.

2025 Q4

Phase I preparation for lead MDC/FDC combo trials (dual path); Redunera partner-facing clinical logic sandbox preparation.

2026 H1

Aim: First Moleculogic IND filed; Tier 3 sandbox partners onboarded.

Partner with MetalDrug

Moleculogic compounds are logic-verified, entropy-stabilized, and regulation-aware. We welcome clinical development partners, biotech acquirers, and licensing inquiries for both early- and late-stage blueprints.